Factor XIII (13) deficiency is an inherited bleeding disorder caused when person’s body doesn’t produce enough of a protein in the blood (factor XIII or FXIII) which helps blood clot or the factor XIII doesn’t work properly. It is very rare, affecting approximately one in 1,000,000 people. Usually both parents have the gene alteration causing the disorder and have passed it onto their child. It affects both males and females.
Links to selected resources:
What Is Factor XIII Deficiency?
(World Federation of Hemophilia)
Explains the causes of this blood disorder, its symptoms, diagnosis and treatment.
Factor XIII deficiency
(Canadian Hemophilia Society, 2001)
Explains how factor XIII deficiency is passed on, what causes it, diagnosis, symptoms, treatments, preventing and treating bleeds, issues relating to women, pregnancy and fertility, lifestyle and vaccinations.
Factor XIII deficiency
(National Hemophilia Foundation, USA)
Source: What are rare clotting factor deficiencies? World Federation of Hemophilia, Montreal, Canada, 2023.
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